COURSE Pharmacokinetics

Why Pharmacokinetics?

Pharmacokinetics (PK) is generally referred to as ‘what the body does to the drug’ versus ‘what the drug does to the body’ (pharmacodynamics [PD]). Pharmacokinetics describes the fate, or time course, of an administered drug within the body. The physiological processes that determine the time course of the drug are Absorption, Distribution, Metabolism and Elimination (ADME). Both the desired effects and undesired effects of a drug are related to the drug levels in the body. The pharmacokinetic properties of a drug determine these levels. Ultimately, the optimal dose and dosing regimen to reach the desired or therapeutic drug levels are determined by means of pharmacokinetics.

This course will focus on the physiochemical properties underlying the pharmacokinetics of a drug, will give insight in the calculation and interpretation of the pharmacokinetic parameters and will also explain the importance and application of pharmacokinetics in preclinical and clinical drug development.

Who should attend?

You are interested in pharmacokinetics (or toxicokinetics), either because you started a career in drug development or in pharmacokinetics, you regularly interact with others working in pharmacokinetics, or simply because you want to broaden your knowledge on this topic. 


During this course you will get familiar with at least the following subjects:

Day 1

  • Understanding of biological processes underlying pharmacokinetics

  - Absorption, including passive diffusion and active drug transport
  - Distribution, including tissue distribution and plasma protein binding
  - Metabolism, including enzymatic transformation, inhibition and induction
  - Elimination, including renal excretion

  • Interpreting volume of distribution and clearance

Day 2

  • Calculation and interpretation of pharmacokinetic parameters

  - Pharmacokinetics after a single IV dose
  - Pharmacokinetics after an extravascular dose
  - Pharmacokinetics after repeated dosing
  - Urinary pharmacokinetic parameters
  - Linear versus non-linear pharmacokinetics


Day 3

  • The role of pharmacokinetics in preclinical and clinical drug development
  • Pharmacokinetics in practice: Case study
  • General introduction into pharmacokinetic / pharmacodynamic modeling


This course will be a mixture of theoretical background, real-life examples and practical exercises.

The result

Upon completion of this course you will be familiar with the pharmacokinetic concepts and the underlying physiochemical processes. You will be able to effectively interpret pharmacokinetic information and put it into the context of drug development.


After this course you will receive a certificate of participation.


The costs of this course will be € 1,850.- (excl. VAT) for three days.
For attendees from universities, academic institutions or governmental authorities there will be a reduced fee of € 950.- (excl. VAT).

Timing & Location

This course consists of three days and is scheduled on November 8-10, 2017 at Kinesis Pharma, Breda, The Netherlands. The maximum desired limit is 25 participants.

Information & Registration

For more information, contact us . For registration, click here.

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